VIAGRA - AN OVERVIEW

Sildenafil can be a strong and selective inhibitor of cGMP-particular phosphodiesterase form five (PDE5), and that is liable for degradation of cGMP during the corpus cavernosum. The molecular construction of sildenafil is comparable to that of cGMP and acts as being a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cG